A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis.Histology revealed changes consistent with chronic viral infection and read more culture grew herpes simplex virus 2 (HSV-2).The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy.Urology excised the mass and the defect was repaired primarily with good cosmetic result.Post-operative pathology confirmed HSV-2 despite the unusual appearance sex shop arles of the lesion consisting of nodular mass without gross ulceration.